Glucagon-like peptide analogues for type 2 diabetes mellitus
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چکیده
منابع مشابه
Glucagon-like peptide analogues for type 2 diabetes mellitus: systematic review and meta-analysis
BACKGROUND Glucagon-like peptide analogues are a new class of drugs used in the treatment of type 2 diabetes that mimic the endogenous hormone glucagon-like peptide 1 (GLP-1). GLP-1 is an incretin, a gastrointestinal hormone that is released into the circulation in response to ingested nutrients. GLP-1 regulates glucose levels by stimulating glucose-dependent insulin secretion and biosynthesis,...
متن کامل[Glucagon-like peptide-1 based therapy for type 2 diabetes].
BACKGROUND Incidence of type 2 diabetes mellitus (T2DM) has increased in young people in recent years and new therapies are required for its effective treatment. Glucagon-like peptide 1 (GLP-1) is a potent blood glucose-lowering hormone produced in the L cells of the intestine. It may be potentially effective in the treatment of hyperglycemia in patients with T2DM. DATA SOURCES PubMed databas...
متن کاملGlucagon - like peptide 1 : new therapies for Type 2 diabetes
June 2004 Volume 49 Issue 2 If GIP and GLP-1 are missing or inactive, the release of insulin is reduced, and a higher rise in blood glucose levels will therefore be expected. In people with Type 2 diabetes, the hormone GIP no longer acts on insulin release and/or blood glucose.The exact reasons are not known.2 In contrast, GLP-1 is able to normalize the levels of blood glucose in Type 2 diabete...
متن کاملEFFECTS OF AEROBIC TRAINING ON DIPEPTIDYL PEPTIDASE-4 AND GLUCAGON-LIKE PEPTIDE-1 IN OBESE WOMEN WITH TYPE 2 DIABETES
Background: Obesity increases the risk of developing type 2 diabetes with regard to the hormones involved. The purpose of this quasi-experimental study was to investigate the effect of aerobic exercise on Dpp-4 and GLP-1 in obese women with type 2 diabetes. Methods: From among obese women with type-2 diabetes mellitus 35-50 years old referred to the Diabetes Association of Saveh, 20 people wer...
متن کاملSerum Glucagon-Like Peptide-1 Changes in Women with Type 2 Diabetes Following a Four Weeks Aerobic Exercise
Objective: The objective of this study was to investigate the effect of four weeks aerobic training on serum glucagon-like peptide-1 (GLP-1) in women with type 2 diabetes mellitus (T2DM). Materials and Methods: Twenty T2DM patients (33-53 years) were randomly assigned into control (n=10) and experimental (n=10) groups. The main intervention included running on treadmill, reaching 55 to 80% o...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2011
ISSN: 1465-1858
DOI: 10.1002/14651858.cd006423.pub2